Interdependence of initial cell density, drug concentration and exposure time revealed by real-time impedance spectroscopic cytotoxicity assay-Reference-Cited by-同舟云学术

Interdependence of initial cell density, drug concentration and exposure time revealed by real-time impedance spectroscopic cytotoxicity assay

Published:2015 Issue:10 Volume:140 Page:3623-3629
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Caviglia C.¹²³⁴,Zór K.¹²³⁴,Canepa S.¹²³⁴,Carminati M.⁵⁶⁷⁸⁹,Larsen L. B.¹²³⁴,Raiteri R.¹⁰¹¹¹²¹³¹⁴,Andresen T. L.¹²³⁴,Heiskanen A.¹²³⁴,Emnéus J.¹²³⁴

Affiliation:

1. Department of Micro- and Nanotechnology

2. Technical University of Denmark

3. Kgs. Lyngby

4. Denmark

5. Dipartimento di Elettronica

6. Informazione e Bioingegneria

7. Politecnico di Milano

8. Milan

9. Italy

10. Department of Informatics

11. Bioengineering

12. Robotics

13. and System Engineering

14. University of Genova

Abstract

The impedance-based drug toxicity assay reveals the effect of cancer drugs, showing the interdependence of the drug exposure time, concentration, and cell density.

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/AN/C5AN00097A

Reference44 articles.

1. Metastatic Cancer Cell

2. Determining the optimal dose in the development of anticancer agents

3. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

4. Comparisons of two in vitro cytotoxicity assays—The neutral red (NR) and tetrazolium MTT tests

5. The sensitivity and specificity of the MTS tetrazolium assay for detecting the in vitro cytotoxicity of 20 chemicals using human cell lines

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