Influence of supramolecular encapsulation of camptothecin by cucurbit[7]uril: reduced toxicity and preserved anti-cancer activity-Reference-Cited by-同舟云学术

Influence of supramolecular encapsulation of camptothecin by cucurbit[7]uril: reduced toxicity and preserved anti-cancer activity

Published:2016 Issue:7 Volume:7 Page:1392-1397
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Yang Xue¹²³⁴⁵,Wang Ziyi¹²³⁴⁵,Niu Yanan¹²³⁴⁵,Chen Xiuping¹²³⁴⁵,Lee Simon M. Y.¹²³⁴⁵,Wang Ruibing¹²³⁴⁵

Affiliation:

1. State Key Laboratory of Quality Research in Chinese Medicine

2. Institute of Chinese Medical Sciences

3. University of Macau

4. Macau

5. China

Abstract

Encapsulation of camptothecin by cucurbit[7]uril significantly inhibited the systemic toxicities of the free drug, while maintaining its antitumor/anti-angiogenic activities.

Funder

Universidade de Macau

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/MD/C6MD00239K

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4. Cytocidal Activities of Topoisomerase 1 Inhibitors and 5-Azacytidine against Pheochromocytoma/Paraganglioma Cells in Primary Human Tumor Cultures and Mouse Cell Lines

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