Defined topologically-complex protein matrices to manipulate cell shape via three-dimensional fiber-like patterns
Author:
Affiliation:
1. Department of Biomedical Engineering
2. College of Engineering
3. University of Michigan
4. Ann Arbor, USA
5. Biointerfaces Institute
6. Department of Mechanical Engineering
7. Department of Materials Science & Engineering
Abstract
We develop a technique to generate well-defined adhesive micropatterns on topologically complex substrates, enabling the culture of individual cells in precisely-controlled, three-dimensional adhesive microstructures.
Funder
Institut national de la santé et de la recherche médicale
Natural Sciences and Engineering Research Council of Canada
Publisher
Royal Society of Chemistry (RSC)
Subject
Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering
Link
http://pubs.rsc.org/en/content/articlepdf/2014/LC/C4LC00122B
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