Significantly improved radiochemical yields in gaseous tritium reactions by iridium(<scp>i</scp>)-catalyzed hydrogen isotope exchange-Reference-Cited by-同舟云学术

Significantly improved radiochemical yields in gaseous tritium reactions by iridium(i)-catalyzed hydrogen isotope exchange

Published:2022 Issue:12 Volume:24 Page:4824-4829
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Morawietz Patrick¹,Weck Remo¹,Scholte Andrew A.²,Atzrodt Jens³,Güssregen Stefan¹,Derdau Volker¹^ORCID

Affiliation:

1. Sanofi-Aventis Deutschland GmbH, R&D, Integrated Drug Discovery, Industriepark Höchst, 65926 Frankfurt am Main, Germany

2. Sanofi Waltham, R&D, Integrated Drug Discovery, 153 2nd Ave., Waltham, MA02451, USA

3. Sanofi-Aventis Deutschland GmbH, Hub Management Office, Industriepark Höchst, 65926 Frankfurt, Germany

Abstract

Hydrogen isotope exchange reactions with iridium(i) catalyst [(COD)Ir(IMes)(PPh3)]X 2 with significantly increased (up to 7 fold) radiochemical yields (RCY) in tritium gas reactions are reported.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/GC/D2GC00534D

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