The Future of (Radio)‐Labeled Compounds in Research and Development within the Life Science Industry

Author:

Derdau Volker1ORCID,Elmore Charles S.2ORCID,Hartung Thomas3,McKillican Bruce4,Mejuch Tom5,Rosenbaum Claudia5,Wiebe Christine5

Affiliation:

1. Sanofi-Aventis Deutschland GmbH Research & Development Integrated Drug Discovery Isotope Chemistry Industriepark Höchst, G876 65926 Frankfurt am Main Germany

2. Early Chemical Development Pharmaceutical Sciences, R&D AstraZeneca Mölndal Sweden

3. Pharma Research and Early Development F. Hoffmann-La Roche Ltd Basel Switzerland

4. Syngenta Crop Protection LLC North America Product Safety (retired) USA

5. BASF SE Agricultural Solutions Ludwigshafen Germany

Abstract

AbstractIn this review the applications of isotopically labeled compounds are discussed and put into the context of their future impact in the life sciences. Especially discussing their use in the pharma and crop science industries to follow their fate in the environment, in vivo or in complex matrices to understand the potential harm of new chemical structures and to increase the safety of human society.

Publisher

Wiley

Subject

General Chemistry,Catalysis

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