Assessing a sustainable manufacturing route to lapatinib-Reference-Cited by-同舟云学术

Assessing a sustainable manufacturing route to lapatinib

Published:2022 Issue:11 Volume:7 Page:2420-2426
ISSN:2058-9883
Container-title:Reaction Chemistry & Engineering
language:en
Short-container-title:React. Chem. Eng.

Author:

Stark Roderick T.¹,Pye Dominic R.¹,Chen Wenyi¹,Newton Oliver J.¹^ORCID,Deadman Benjamin J.²^ORCID,Miller Philip W.¹^ORCID,Panayides Jenny-Lee³^ORCID,Riley Darren L.⁴^ORCID,Hellgardt Klaus⁵,Hii King Kuok (Mimi)¹²^ORCID

Affiliation:

1. Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, 82, Wood Lane, London W12 0BZ, UK

2. Centre for Rapid Online Analysis of Reactions (ROAR), Molecular Sciences Research Hub, 82, Wood Lane, London W12 0BZ, UK

3. Pharmaceutical Technologies, Future Production: Chemicals, Council for Scientific & Industrial Research (CSIR), Meiring Naude Rd, Brummeria, Pretoria, 0184, South Africa

4. Department of Chemistry, Faculty of Natural and Agricultural Sciences, University of Pretoria, Lynnwood Rd, Hatfield, Pretoria, 0002, South Africa

5. Department of Chemical Engineering, Imperial College London, Exhibition Road, South Kensington, London SW7 2AZ, UK

Abstract

A synthetic route to an anti-cancer drug, lapatinib, was devised to support the development of a sustainable manufacturing process in South Africa.

Funder

Global Challenges Research Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

Fluid Flow and Transfer Processes,Process Chemistry and Technology,Chemical Engineering (miscellaneous),Chemistry (miscellaneous),Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/RE/D2RE00267A

Reference23 articles.

1. Genetic Predisposition to Breast Cancer: Past, Present, and Future

2. Global, regional, national burden of breast cancer in 185 countries: evidence from GLOBOCAN 2018

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