Classic vs. C–H functionalization strategies in the synthesis of APIs: a sustainability comparison

Author:

Ferlin Francesco1ORCID,Brufani Giulia1,Rossini Gabriele1,Vaccaro Luigi1ORCID

Affiliation:

1. Laboratory of Green S.O.C., Dipartimento di Chimica Biologia e Biotecnologie, Università degli Studi di Perugia, Via Elce di Sotto, 8, 06123 Perugia, Italy

Abstract

This review present case studies analyzed in terms of waste production and environmental/safety hazard aiming at quantify whether the adoption of C–H functionalization technology is actually the most effective strategy compared to classic approaches.

Funder

Università degli Studi di Perugia

Consumer Programme

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

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