CuIIcomplex of emodin with improved anticancer activity as demonstrated by its performance on HeLa and Hep G2 cells-Reference-Cited by-同舟云学术

CuIIcomplex of emodin with improved anticancer activity as demonstrated by its performance on HeLa and Hep G2 cells

Published:2017 Issue:66 Volume:7 Page:41403-41418
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Mandal Bitapi¹²³⁴,Singha Soumen⁵²³⁴,Dey Sanjoy Kumar⁵⁶⁴,Mazumdar Swagata⁷²³⁴,Kumar Sanjay⁵²³⁴,Karmakar Parimal⁷²³⁴,Das Saurabh¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry (Inorganic Section)

2. Jadavpur University

3. Kolkata-700032

4. India

5. Department of Physics

6. NITMAS

7. Department of Life Science and Biotechnology

Abstract

Structure of Cu^IIcomplex of emodin was solved from PXRD data. [Cu^II(emod)₂]²⁻binds DNA better than emodin. Thermodynamic parameters for binding were found. Complex performs better than emodin on HeLa & Hep G2 cells; not affecting WI 38 normal cells.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/RA/C7RA06696A

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