Use of kefir peptide (Kef-1) as an emerging approach for the treatment of oxidative stress and inflammation in 2K1C mice

Author:

Aires Rafaela1ORCID,Gobbi Amorim Fernanda2ORCID,Côco Larissa Zambom3ORCID,da Conceição Amanda Pompermayer3ORCID,Zanardo Tadeu Ériton Caliman45ORCID,Taufner Gabriel Henrique45ORCID,Nogueira Breno Valentim45ORCID,Vasquez Elisardo Corral3ORCID,Melo Costa Pereira Thiago36ORCID,Campagnaro Bianca Prandi3ORCID,dos Santos Meyrelles Silvana1ORCID

Affiliation:

1. Laboratory of Translational Physiology, Physiological Sciences Graduate Program, Federal University of Espirito Santo (UFES), Vitoria, Brazil

2. Laboratory of Mass Spectrometry, Department of Chemistry, University of Liège, Liège, Belgium

3. Laboratory of Translational Physiology and Pharmacology, Pharmaceutical Sciences Graduate Program, Vila Velha University (UVV), Vila Velha, Brazil

4. Biotechnology Graduate Program, Rede Nordeste de Biotecnologia (RENORBIO), Vitória, Brazil

5. Tissue Engineering Core, Department of Morphology, Federal University of Espírito Santo, Vitória, Brazil

6. Federal Institute of Education, Science and Technology (IFES), Vila Velha, ES, Brazil

Abstract

In this study, an ACE inhibitor peptide synthesized from probiotic Kefir showed expressive biological activities in 2K1C hypertension.

Funder

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Fundação Estadual de Amparo à Pesquisa do Estado do Espírito Santo

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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