Production of indole antibiotics induced by exogenous gene derived from sponge metagenomes
Author:
Affiliation:
1. Graduate School of Pharmaceutical Sciences
2. The University of Tokyo
3. Tokyo 113-0033
4. Japan
Abstract
Sponge metagenomes are accessible genetic sources containing genes and gene clusters responsible for the biosynthesis of sponge-derived bioactive natural products.
Publisher
Royal Society of Chemistry (RSC)
Subject
Molecular Biology,Biotechnology
Link
http://pubs.rsc.org/en/content/articlepdf/2015/MB/C5MB00131E
Reference25 articles.
1. Brominated acetylenic fatty acids from Xestospongia sp., a marine spongebacteria association
2. Metagenomic Analysis Reveals Diverse Polyketide Synthase Gene Clusters in Microorganisms Associated with the Marine Sponge Discodermia dissoluta
3. Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei
4. Calyculin biogenesis from a pyrophosphate protoxin produced by a sponge symbiont
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