Accurate selected ion flow tube mass spectrometry quantification of ethylene oxide contamination in the presence of acetaldehyde

Author:

Swift Stefan J.1ORCID,Dryahina Kseniya1ORCID,Lehnert Ann-Sophie2,Demarais Nicholas3,Langford Vaughan S.3ORCID,Perkins Mark J.4,Silva Leslie P.5,Omezzine Gnioua Maroua16ORCID,Španěl Patrik1ORCID

Affiliation:

1. J. Heyrovský Institute of Physical Chemistry of the CAS, v. v. i., Dolejškova 2155/3, Prague 182 23, Czechia

2. Syft Technologies, Hilperstraße 31, Darmstadt 64295, Germany

3. Syft Technologies, 68 Saint Asaph Street, Christchurch Central City, Christchurch 8011, New Zealand

4. Element Lab Solutions, Unit 4, Wellbrook Court, Girton Rd, Girton, Cambridge CB3 0NA, UK

5. Syft Technologies, 675N Euclid St #627, Anaheim, CA 92801, USA

6. Faculty of Mathematics and Physics, Charles University, Ke Karlovu 3, Prague 121 16, Czechia

Abstract

Rate coefficients and product ion branching ratios were obtained for the gas phase reactions of the H3O+, NO+, OH and O˙ ions with ethylene oxide and acetaldehyde.

Funder

Grantová Agentura České Republiky

Akademie Věd České Republiky

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Reference45 articles.

1. Manufacture and Uses of Ethylene Oxide and Ethylene Glycol

2. Ethylene oxide in foods: current approach to the risk assessment and practical considerations based on the European food business operator perspective

3. A. C.Leslie Silva , Chad Bastian, Christopher Williams, Zachary Morseth, and Elliott Franco, Simple, Rapid Analysis of Ethylene Oxide in a Polysorbate 80 Excipient Using SIFT-MS , 2023 , https://bit.ly/3QLWRmC

4. O.Frost , Quantitative Ethylene Oxide Analysis in Polysorbate 80 , 2023 , https://www.azom.com/article.aspx?ArticleID=22192

5. Ethylene oxide sterilization of medical devices: A review

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