Inhibition of the NF-κB and mTOR targets by urolithin A attenuates <scp>d</scp>-galactose-induced aging in mice-Reference-Cited by-同舟云学术

Inhibition of the NF-κB and mTOR targets by urolithin A attenuates d-galactose-induced aging in mice

Published:2023 Issue:23 Volume:14 Page:10375-10386
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Zhang Mengwei¹²,Tang Xin¹²^ORCID,Mao Bingyong¹²,Zhang Qiuxiang¹²^ORCID,Zhao Jianxin¹²^ORCID,Chen Wei¹²³^ORCID,Cui Shumao¹²

Affiliation:

1. State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, Jiangsu 214122, P. R. China

2. School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, P. R. China

3. National Engineering Research Center for Functional Food, Jiangnan University, Wuxi, Jiangsu 214122, P. R. China

Abstract

The dose-effect relationship between colonic perfusion of urolithin A and its anti-aging effect was investigated. Urolithin A inhibits NF-κB and mTOR targets to attenuate d-galactose-induced motor and cognitive decline.

Funder

Collaborative Innovationcenter of Food Safety and Quality Control in Jiangsu Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/FO/D3FO03847E

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