Palladium-catalyzed cyclizative cross coupling of ynone oximes with 2-haloaryl <i>N</i>-acrylamides for isoxazolyl indoline bis-heterocycles-Reference-Cited by-同舟云学术

Palladium-catalyzed cyclizative cross coupling of ynone oximes with 2-haloaryl N-acrylamides for isoxazolyl indoline bis-heterocycles

Published:2022 Issue:13 Volume:20 Page:2609-2614
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Kotipalli Ramesh¹²,Nagireddy Attunuri¹²^ORCID,Reddy Maddi Sridhar¹²^ORCID

Affiliation:

1. Department of OSPC, CSIR-Indian Institute of Chemical Technology, Habsiguda, Hyderabad 500007, India

2. Academy of Scientific and Innovative Research, Ghaziabad 201002, India

Abstract

We demonstrated a dual-cyclizative coupling of ynone oxime ethers with acrylamides for the synthesis of isoxazolyl 2-oxindoles. The cascade is triggered by a palladium(ii)-catalyzed ynone oxime ether cyclization, and is completed by a Heck-type coupling.

Funder

University Grants Commission

Council of Scientific and Industrial Research, India

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/OB/D2OB00065B

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