Self-assembled iRGD-R7-LAHP-M nanoparticle induced sufficient singlet oxygen and enhanced tumor penetration immunological therapy

Abstract

(a) Schematic illustration for the preparation of iRGD-R7-LAHP-M NPs. (b) The prepared NPs penetrated into the deep tumor, and released LAHP and metal ions in acid pH, inducing singlet oxygen-mediated cell death and evoking immunogenic cell death.