Ozonolysis of neem oil: preparation and characterization of potent antibacterial agents against multidrug resistant bacterial strains

Author:

de Oliveira Paola12345,de Almeida Nathália6789,Conda-Sheridan Martin6789ORCID,Apparecido Rafael do Prado12345,Micheletti Ana Camila12345,Carvalho Nadia Cristina10345,dos Santos Edson dos Anjos1112345,Marques Maria Rita1112345,de Arruda Eduardo1314155,Alcantara Glaucia Braz12345,de Oliveira Lincoln Carlos12345,de Lima Dênis12345,Beatriz Adilson12345ORCID

Affiliation:

1. Instituto de Química – INQUI

2. Universidade Federal do Mato Grosso do Sul

3. Cidade Universitária

4. Campo Grande

5. Brazil

6. University of Nebraska Medical Center – UNMC

7. Department of Pharmaceutical Sciences

8. Omaha

9. USA

10. Núcleo do Hospital Universitário da Universidade Federal do Mato Grosso do Sul NHU/UFMS

11. Centro de Ciências Biológicas e da Saúde

12. Universidade Federal de Mato Grosso do Sul

13. Faculdade de Ciência Exatas e Tecnologia (FACET)

14. Universidade Federal da Grande Dourados (UFGD)

15. Dourados

Abstract

Neem ozonated oils showed excellent broad-spectrum antimicrobial activity against standard E. faecalis, clinical vancomycin resistant E. faecium, clinical multiresistant K. pneumoniae (KPC), and S. aureus (MRSA and standard).

Funder

Fundação de Apoio ao Desenvolvimento do Ensino, Ciência e Tecnologia do Estado de Mato Grosso do Sul

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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