Development and design of the tertiary amino effect reaction for DNA-encoded library synthesis-Reference-Cited by-同舟云学术

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Development and design of the tertiary amino effect reaction for DNA-encoded library synthesis

Published:2016 Issue:7 Volume:7 Page:1316-1322
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Tian Xia¹²³,Basarab Gregory S.⁴⁵²³⁶,Selmi Nidhal⁷⁸⁹¹⁰¹¹,Kogej Thierry⁷⁸⁹¹⁰¹¹,Zhang Ying¹²³,Clark Matthew¹²³,Goodnow Jr. Robert A.⁷⁵²³

Affiliation:

1. X-Chem, Inc.

2. Waltham

3. USA

4. AstraZeneca Infection

5. Innovative Medicines and Early Development Biotech Unit

6. Department of Chemistry

7. AstraZeneca Discovery Sciences

8. Innovative Medicines and Early Development

9. Biotech Unity

10. SE-431 83 Mölndal

11. Sweden

Abstract

The tertiary amino effect reaction was explored and developed for application to DNA-encoded library synthesis.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/MD/C6MD00088F

Reference41 articles.

1. 20 years of DNA-encoded chemical libraries

2. DNA tags help the hunt for drugs

3. Phagemid Encoded Small Molecules for High Throughput Screening of Chemical Libraries

4. Encoded self-assembling chemical libraries

5. DNA-encoded chemical libraries

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1. Heterocyclization vs Coupling Reactions: A DNA-Encoded Libraries Case;Journal of Organic and Pharmaceutical Chemistry;2023-06-03

2. DNA-Compatible Diversification of Indole π-Activated Alcohols via a Direct Dehydrative Coupling Strategy;Organic Letters;2022-01-20

3. Development of on-DNA vinyl sulfone synthesis for DNA-encoded chemical libraries;Organic Chemistry Frontiers;2022

4. Other Fused Azetidines, Azetines and Azetes;Comprehensive Heterocyclic Chemistry IV;2022

5. DNA-Compatible Nitro Reduction and Synthesis of Benzimidazoles;Methods in Molecular Biology;2022

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