Prospecting for new bacterial metabolites: a glossary of approaches for inducing, activating and upregulating the biosynthesis of bacterial cryptic or silent natural products

Author:

Zarins-Tutt Joseph Scott1234,Barberi Tania Triscari1234,Gao Hong1234,Mearns-Spragg Andrew567,Zhang Lixin89101112,Newman David J.13141516,Goss Rebecca Jane Miriam1234

Affiliation:

1. School of Chemistry

2. University of St Andrews

3. St Andrews

4. UK

5. Aquapharm Biodiscovery Ltd.

6. European Centre for Marine Biotechnology

7. PA37 1QA UK

8. CAS Key Laboratory of Pathogenic Microbiology and Immunology

9. Institute of Microbiology

10. Chinese Academy of Sciences

11. Beijing

12. China

13. Frederick National Laboratories for Cancer Research

14. Natural Products Branch

15. Frederick

16. USA

Abstract

Over the centuries, microbial secondary metabolites have played a central role in the treatment of human diseases and have revolutionised the pharmaceutical industry.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

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