A factor VIII-derived peptide enables von Willebrand factor (VWF)-binding of artificial platelet nanoconstructs without interfering with VWF-adhesion of natural platelets-Reference-Cited by-同舟云学术

A factor VIII-derived peptide enables von Willebrand factor (VWF)-binding of artificial platelet nanoconstructs without interfering with VWF-adhesion of natural platelets

Published:2014 Issue:9 Volume:6 Page:4765-4773
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Haji-Valizadeh Hassan¹²³,Modery-Pawlowski Christa L.¹²³,Sen Gupta Anirban¹²³

Affiliation:

1. Department of Biomedical Engineering

2. Case Western Reserve University

3. Cleveland, USA

Abstract

Co-decoration of liposomal nanoconstructs with FVIII-derived VWF-binding-peptides (VBP) and active platelet-clustering fibrinogen-mimetic-peptides (FMP) allows platelet-mimetic VWF-adhesion and platelet aggregation.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2014/NR/C3NR06400J

Reference37 articles.

1. von Willebrand factor: at the crossroads of bleeding and thrombosis

2. von Willebrand factor to the rescue

3. Adhesion Mechanisms in Platelet Function

4. NEW CYTOPLASMIC COMPONENTS IN ARTERIAL ENDOTHELIA

5. von Willebrand Factor: More Than a Regulator of Hemostasis and Thrombosis

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