Reinforcement of polymeric nanoassemblies for ultra-high drug loadings, modulation of stiffness and release kinetics, and sustained therapeutic efficacy-Reference-Cited by-同舟云学术

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Reinforcement of polymeric nanoassemblies for ultra-high drug loadings, modulation of stiffness and release kinetics, and sustained therapeutic efficacy

Published:2018 Issue:18 Volume:10 Page:8360-8366
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Ekladious Iriny¹²³⁴^ORCID,Liu Rong⁵⁶³⁴^ORCID,Varongchayakul Nitinun¹²³⁴^ORCID,Mejia Cruz Luis A.⁷⁸⁹⁴^ORCID,Todd Daniel A.⁷⁸⁹⁴^ORCID,Zhang Heng¹²³⁴^ORCID,Oberlies Nicholas H.⁷⁸⁹⁴^ORCID,Padera Robert F.¹⁰⁶³⁴^ORCID,Colson Yolonda L.⁵⁶³⁴^ORCID,Grinstaff Mark W.¹²³⁴^ORCID

Affiliation:

1. Departments of Biomedical Engineering and Chemistry

2. Boston University

3. Boston

4. USA

5. Department of Surgery

6. Brigham and Women's Hospital

7. Department of Chemistry and Biochemistry

8. University of North Carolina at Greensboro

9. Greensboro

10. Department of Pathology

Abstract

Beyond the MTD and LD₅₀, use of novel ultra-high drug loaded nanoparticles.

Funder

National Science Foundation

Brigham and Women's Hospital

Boston University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2018/NR/C8NR01978A

Reference56 articles.

1. Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release

2. Nanoparticle therapeutics: an emerging treatment modality for cancer

3. Strategies in the design of nanoparticles for therapeutic applications

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