Zn(ii) complexes with thiazolyl–hydrazones: structure, intermolecular interactions, photophysical properties, computational study and anticancer activity

Author:

Araškov Jovana B.1,Višnjevac Aleksandar2ORCID,Popović Jasminka2ORCID,Blagojević Vladimir3,Fernandes Henrique S.45ORCID,Sousa Sérgio F.45ORCID,Novaković Irena6,Padrón José M.7ORCID,Holló Berta Barta8,Monge Miguel9ORCID,Rodríguez-Castillo María9,López-de-Luzuriaga José M.9ORCID,Filipović Nenad R.10,Todorović Tamara R.1ORCID

Affiliation:

1. University of Belgrade – Faculty of Chemistry, Studentski trg 12-16, 11000 Belgrade, Serbia

2. Division of Physical Chemistry, Institute Ruđer Bošković, Bijenička cesta 54, 10000 Zagreb, Croatia

3. Institute of Technical Sciences of the Serbian Academy of Sciences and Arts, Knez Mihailova 35/IV, 11000 Belgrade, Serbia

4. UCIBIO – Applied Molecular Biosciences Unit, BioSIM – Department of Biomedicine, Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal

5. Associate Laboratory i4HB – Institute for Health and Bioeconomy, Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal

6. Institute of Chemistry, Technology and Metallurgy, University of Belgrade, Njegoševa 12, 11000, Belgrade, Serbia

7. BioLab, Instituto Universitario de Bio-Orgánica “Antonio González”, Universidad de La Laguna, 38071 La Laguna, Spain

8. University of Novi Sad, Faculty of Sciences, Trg Dositeja Obradovića 4, 21000 Novi Sad, Serbia

9. Departamento de Química, Universidad de La Rioja, Centro de Investigación en Síntesis Química (CISQ), Complejo Científico-Tecnológico, 26004 Logroño, Spain

10. University of Belgrade – Faculty of Agriculture, Nemanjina 6, 11000 Belgrade, Serbia

Abstract

Title ligands and their symmetrical octahedral complexes are not photoluminescent, contrary to other synthesized asymmetrical complexes. In comparison to the ligands, the complexes showed improved antiproliferative activity and lower toxicity.

Funder

Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja

Fundação para a Ciência e a Tecnologia

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Materials Science,General Chemistry

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