An electron-accepting half-sandwich iridium(<scp>iii</scp>) complex for the treatment of hypoxic tumors <i>via</i> synergetic chemo- and phototherapy-Reference-Cited by-同舟云学术

An electron-accepting half-sandwich iridium(iii) complex for the treatment of hypoxic tumors via synergetic chemo- and phototherapy

Published:2024 Issue:2 Volume:11 Page:436-450
ISSN:2052-1553
Container-title:Inorganic Chemistry Frontiers
language:en
Short-container-title:Inorg. Chem. Front.

Author:

Yang Yuliang¹,Gao Ya¹,Zhao Jian¹²^ORCID,Gou Shaohua¹²^ORCID

Affiliation:

1. Pharmaceutical Research Center and School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, China

2. Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing 211189, China

Abstract

Here is a red light-responsive half-sandwich iridium(iii) complex designed for treating hypoxic tumors through a synergistic effect involving apoptosis and ferroptosis.

Funder

National Natural Science Foundation of China - State Grid Corporation Joint Fund for Smart Grid

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2024/QI/D3QI02047A

Reference73 articles.

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4. Synthesis, Characterization, and Biological Evaluation of a Porphyrin-Based Photosensitizer and Its Isomer for Effective Photodynamic Therapy against Breast Cancer

5. Photoactivation of Boronic Acid Prodrugs via a Phenyl Radical Mechanism: Iridium(III) Anticancer Complex as an Example

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