Mitochondria-targeting fluorescent molecules for high efficiency cancer growth inhibition and imaging-Reference-Cited by-同舟云学术

Mitochondria-targeting fluorescent molecules for high efficiency cancer growth inhibition and imaging

Published:2019 Issue:34 Volume:10 Page:7946-7951
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Chen Hao¹²³⁴⁵,Wang Jing¹²³⁴⁶,Feng Xin⁶⁷¹⁸⁹,Zhu Mark⁶⁷¹⁸⁹,Hoffmann Simon⁶⁷¹⁸⁹,Hsu Alex⁶⁷¹⁸⁹,Qian Kun⁶⁷¹⁸⁹,Huang Daijuan⁶⁷¹⁸⁹,Zhao Feng⁶⁷¹⁸⁹,Liu Wei¹²³⁴,Zhang Huimao¹²³⁴,Cheng Zhen⁶⁷¹⁸⁹^ORCID

Affiliation:

1. Department of Radiology

2. The First Hospital of Jilin University

3. Changchun

4. China

5. Center for Molecular Imaging Research

6. Molecular Imaging Program at Stanford (MIPS)

7. Bio-X Program

8. Canary Center at Stanford for Cancer Early Detection

9. Stanford University

Abstract

5BMF is a new fluorescent mitochondria-accumulating delocalized lipophilic cations [DLC] that boasts significantly increased anti-cancer effects and low toxicity in comparison to previous DLCs, addressing current hurdles in DLC clinical translation.

Funder

Office of Science

U.S. Department of Energy

National Natural Science Foundation of China

Department of Finance of Jilin Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/SC/C9SC01410A

Reference37 articles.