Computational analysis of binding between benzamide-based derivatives and Abl wt and T315I mutant kinases-Reference-Cited by-同舟云学术

Computational analysis of binding between benzamide-based derivatives and Abl wt and T315I mutant kinases

Published:2016 Issue:88 Volume:6 Page:85355-85366
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Zhou Shengfu¹²³⁴⁵,Tan Shepei¹²³⁴⁵,Fang Danqing⁶⁷⁸⁵,Zhang Rong¹²³⁴⁵,Lin Weicong¹²³⁴⁵,Wu Wenjuan¹²³⁴⁵,Zheng Kangcheng⁹¹⁰¹¹⁵

Affiliation:

1. Department of Physical Chemistry

2. College of Pharmacy

3. Guangdong Pharmaceutical University

4. Guangzhou 510006

5. PR China

6. Department of Cardiothoracic Surgery

7. Affiliated Second Hospital of Guangzhou Medical University

8. Guangzhou 510260

9. School of Chemistry and Chemical Engineering

10. Sun Yat-Sen University

11. Guangzhou 510275

Abstract

An integrated computational study was performed to identify the binding mechanisms of benzamide-based derivatives with Abl_wt/Abl_T315I kinases for designing Abl inhibitors.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA19494J

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