Heterobimetallic platinum(ii) complexes with increased cytotoxicity against ovarian cancer cell lines

Author:

Melounková Lucie12,Syková Miriam3,Jirásko Robert1,Jambor Roman3,Havelek Radim2ORCID,Peterová Eva2,Honzíček Jan4ORCID,Vinklárek Jaromír3ORCID

Affiliation:

1. Department of Analytical Chemistry, Faculty of Chemical Technology, University of Pardubice, Studentská 573, 53210 Pardubice, Czech Republic

2. Department of Medical Biochemistry, Faculty of Medicine in Hradec Králové, Charles University in Prague, Šimkova 870, 500 01 Hradec Králové, Czech Republic

3. Department of General and Inorganic Chemistry, Faculty of Chemical Technology, University of Pardubice, Studentská 573, 53210 Pardubice, Czech Republic

4. Institute of Chemistry and Technology of Macromolecular Materials, Faculty of Chemical Technology, University of Pardubice, Studentská 573, 53210 Pardubice, Czech Republic

Abstract

Two series of heterobimetallic compounds were prepared from the starting complex [cis-L2PtCl2] containing an aminophosphine ligand (L = 2,6-iPr2-C6H3-NHPPh2).

Funder

Univerzita Karlova v Praze

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

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