Polyamidoamine and polyglycerol; their linear, dendritic and linear–dendritic architectures as anticancer drug delivery systems

Author:

Mohammadifar Ehsan12345,Nemati Kharat Ali12345,Adeli Mohsen67895

Affiliation:

1. School of Chemistry

2. University College of Science

3. University of Tehran

4. Tehran

5. Iran

6. Department of Chemistry

7. Faculty of Science

8. Lorestan University

9. Khoramabad

Abstract

This review covers the latest advances in the conjugation of chemotherapeutics such as doxorubicin, paclitaxel, methotrexate, fluorouracil and cisplatin to dendritic polymers, including polyamidoamine dendrimers, hyperbranched polyglycerols and their linear analogues, with a focus on their cytotoxicity, biodistribution and biodegradability.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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