Naphthalimides as anti-cancer agents: systematic synthesis and biological activity along with their encapsulated G0.5 PAMAM dendrimer nanoparticles-Reference-Cited by-同舟云学术

Naphthalimides as anti-cancer agents: systematic synthesis and biological activity along with their encapsulated G0.5 PAMAM dendrimer nanoparticles

Published:2024 Issue:32 Volume:48 Page:14191-14201
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Noshirvani Sharifabad Azita¹^ORCID,Khosravi Alireza¹^ORCID,Shirazi Farshad H.²³,Shaki Hanieh⁴,Farnam Golrokh³,Moghimi Hamid Reza⁵,Kobarfard Farzad⁶

Affiliation:

1. Department of Polymer and Color Engineering, Amirkabir University of Technology (Tehran Polytechnic), Tehran, Iran

2. Department of Toxicology and Pharmacology, Shahid Beheshti School of Pharmacy, Tehran, Iran

3. Pharmaceutical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran

4. Department of Polymer Engineering, Faculty of Engineering, Golestan University, Gorgan, Iran

5. Department of Pharmaceutics and Nanotechnology, Shahid Beheshti School of Pharmacy, Tehran, Iran

6. Department of Medicinal Chemistry, Shahid Beheshti School of Pharmacy, Tehran, Iran

Abstract

Fabrication of six novel naphthalimide derivatives encapsulated within G0.5 PAMAM dendrimer nanoparticles, exhibiting promising anticancer properties through a DNA intercalation mechanism attributed to the planar structure of naphthalimides.

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/NJ/D4NJ02244K

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