Synthesis and application of P,olefin type axially chiral ligands with sec-alkyl groups-Reference-Cited by-同舟云学术

Synthesis and application of P,olefin type axially chiral ligands with sec-alkyl groups

Published:2019 Issue:6 Volume:17 Page:1455-1465
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Mino Takashi¹²³⁴⁵^ORCID,Yamaguchi Daiki¹²³⁴,Masuda Chihiro¹²³⁴,Youda Junpei¹²³⁴,Ebisawa Toshibumi¹²³⁴,Yoshida Yasushi¹²³⁴⁵^ORCID,Sakamoto Masami¹²³⁴⁵^ORCID

Affiliation:

1. Graduate School of Engineering

2. Chiba University

3. Chiba 263-8522

4. Japan

5. Molecular Chirality Research Center

Abstract

Palladium-catalyzed asymmetric allylic substitution with indoles using a chiral ligand 3b, which have fewer hindered substituents such as secondary alkyl groups than 1-adamantyl group, gave desired products (R)-9 with high enantioselectivities (up to 96% ee).

Funder

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/OB/C9OB00075E

Reference37 articles.

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3. R. Noyori , Asymmetric Catalysis in Organic Synthesis , John Wiley & Sons , New York , 1994