Affiliation:
1. School of Resources and Environment Harbin Institute of Technology Harbin 150080 China
2. Department of Chemistry Guangdong Provincial Key Laboratory of Catalysis College of Science Southern University of Science and Technology Guangming Advanced Research Institute Southern University of Science and Technology Shenzhen 518055 China
Abstract
AbstractWith chiral amine (DHQD)2PHAL as nucleophilic catalyst, asymmetric synthesis of enantioenriched 3‐allylindoles was achieved from indolone‐2‐imines and MBH carbonates. Compared with our previous chiral phosphine catalysis, the chiral amine had exactly the opposite effect in terms of enantioselectivity. Importantly, we could obtain each enantiomer by adjusting the catalyst system.
Funder
National Natural Science Foundation of China
Guangdong Provincial Key Laboratory Of Catalysis