Mono- and three-tailed sugar and iminosugar decorated benzenesulfonamide carbonic anhydrase inhibitors-Reference-Cited by-同舟云学术

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Mono- and three-tailed sugar and iminosugar decorated benzenesulfonamide carbonic anhydrase inhibitors

Published:2023 Issue:21 Volume:21 Page:4491-4503
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Davighi Maria Giulia¹^ORCID,Matassini Camilla¹^ORCID,Goti Andrea¹^ORCID,Ferraroni Marta¹^ORCID,Angeli Andrea²^ORCID,Supuran Claudiu T.²^ORCID,Cardona Francesca¹^ORCID

Affiliation:

1. Dipartimento di Chimica “Ugo Schiff” DICUS, Università degli Studi di Firenze, Via della Lastruccia 3-13, 50019 Sesto Fiorentino (FI), Italy

2. Dipartimento Neurofarba, Sezione di Scienze Farmaceutiche e Nutraceutiche, Università degli Studi di Firenze, 50019 Sesto Fiorentino (FI), Italy

Abstract

The synthesis and enzymatic activity of benzenesulfonamide hCA inhibitors tailored with mono- and three-tailed sugars and iminosugars are described in this work.

Funder

Fondazione Cassa di Risparmio di Firenze

Ministero dell’Istruzione, dell’Università e della Ricerca

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB00529A

Reference50 articles.

1. Carbonic anhydrase: chemistry, physiology, and inhibition

2. Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

3. Review Article

4. Exploring the multiple binding modes of inhibitors to carbonic anhydrases for novel drug discovery

5. Carbonic anhydrases in metazoan model organisms: molecules, mechanisms, and physiology

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