Exploring the multiple binding modes of inhibitors to carbonic anhydrases for novel drug discovery
Author:
Affiliation:
1. Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Florence, Italy
Funder
not funded
Publisher
Informa UK Limited
Subject
Drug Discovery
Link
https://www.tandfonline.com/doi/pdf/10.1080/17460441.2020.1743676
Reference192 articles.
1. Structure and function of carbonic anhydrases
2. Carbonic anhydrases: novel therapeutic applications for inhibitors and activators
3. Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?
4. Interfering with pH regulation in tumours as a therapeutic strategy
5. Exploiting the hydrophobic and hydrophilic binding sites for designing carbonic anhydrase inhibitors
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