Asymmetric chemoenzymatic synthesis of 1,3-diols and 2,4-disubstituted aryloxetanes by using whole cell biocatalysts

Author:

Vitale Paola12345,Perna Filippo Maria12345,Agrimi Gennaro67845,Scilimati Antonio12345,Salomone Antonio91011125,Cardellicchio Cosimo1314245,Capriati Vito12345ORCID

Affiliation:

1. Dipartimento di Farmacia-Scienze del Farmaco

2. Università di Bari “A. Moro”

3. Consorzio C.I.N.M.P.I.S.

4. I-70125 Bari

5. Italy

6. Department of Biosciences

7. Biotechnologies and Biopharmaceutics

8. University of Bari “A. Moro”

9. Dipartimento di Scienze e Tecnologie Biologiche ed Ambientali

10. Università del Salento

11. Prov.le Lecce-Monteroni

12. I-73100 Lecce

13. CNR ICCOM

14. Dipartimento di Chimica

Abstract

A simple and efficient chemoenzymatic approach for the asymmetric synthesis of 1,3-diols and 2,4-disubstituted aryloxetanes has been established.

Funder

Universita degli Studi di Bari Aldo Moro

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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