Auricularia polytricha ethanol crude extract from sequential maceration induces lipid accumulation and inflammatory suppression in RAW264.7 macrophages-Reference-Cited by-同舟云学术

Auricularia polytricha ethanol crude extract from sequential maceration induces lipid accumulation and inflammatory suppression in RAW264.7 macrophages

Published:2021 Issue:21 Volume:12 Page:10563-10570
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Sangphech Naunpun¹^ORCID,Sillapachaiyaporn Chanin²,Nilkhet Sunita²,Chuchawankul Siriporn³⁴^ORCID

Affiliation:

1. Medical Technology, School of Allied Health Sciences, Walailak University, 222 Thaiburi, Thasala, Nakorn Si Thammarat, 80160, Thailand

2. Program in Clinical Biochemistry and Molecular Medicine, Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok, 10330, Thailand

3. Department of Transfusion Medicine and Clinical Microbiology, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok, 10330, Thailand

4. Immunomodulation of Natural Products Research Group, Chulalongkorn University, Bangkok, 10330, Thailand

Abstract

Using LC-MS combine with in silico approch, we predict that 15d-PGJ2-G is a bioactive compound in Auricularia polytricha ethanol crude interacted with PPARγ to regulate lipid accumulation and anti-inflammation in RAW264.7 macrophages.

Funder

Faculty of Allied Health Sciences, Chulalongkorn University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/FO/D0FO02574G

Reference50 articles.

1. Auricularia polytricha aqueous extract supplementation decreases hepatic lipid accumulation and improves antioxidative status in animal model of nonalcoholic fatty liver

2. First demonstration of protective effects of purified mushroom polysaccharide-peptides against fatty liver injury and the mechanisms involved

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4. Mushroom immunomodulatory proteins possess potential thermal/freezing resistance, acid/alkali tolerance and dehydration stability

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