Quantification of recombinant human relaxin-2 (B-29/A-24) in non-pregnant rat plasma using ultra performance liquid chromatography-mass spectrometry-Reference-Cited by-同舟云学术

Quantification of recombinant human relaxin-2 (B-29/A-24) in non-pregnant rat plasma using ultra performance liquid chromatography-mass spectrometry

Published:2014 Issue:7 Volume:6 Page:2072-2079
ISSN:1759-9660
Container-title:Anal. Methods
language:en
Short-container-title:Anal. Methods

Author:

Zhu Xiaoyan¹²³⁴⁵,Liu Jingjing¹²³⁴,Wu Jie¹²³⁴,Cao Rongyue¹²³⁴,Li Taiming¹²³⁴

Affiliation:

1. Minigene Pharmacy Laboratory

2. School of Life Science & Technology

3. China Pharmaceutical University

4. Nanjing, P.R. China

5. Drug Metabolism and Pharmacokinetics Department

Abstract

A sensitive analytical method using ultra performance liquid chromatography-tandem mass spectrometry is developed for the determination of recombinant human relaxin-2 (B-29/A-24) in rats for characterizing pharmacokinetics.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/AY/C3AY42194E

Reference16 articles.

1. Relaxin-3 and receptors in the human and rhesus brain and reproductive tissues

2. Relaxin family peptide receptors – from orphans to therapeutic targets

3. Relaxin Antagonizes Hypertrophy and Apoptosis in Neonatal Rat Cardiomyocytes

4. Relaxin: A pleiotropic hormone

5. Drugs of the future: the hormone relaxin

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