Synthesis of highly substituted 2-spiropiperidines-Reference-Cited by-同舟云学术

Synthesis of highly substituted 2-spiropiperidines

Published:2018 Issue:36 Volume:16 Page:6663-6674
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Griggs Samuel D.¹²³⁴,Thompson Nathan¹²³⁴,Tape Daniel T.⁵⁶⁷⁴,Fabre Marie¹²³⁴,Clarke Paul A.¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. University of York

3. York

4. UK

5. Flexible Discovery Unit

6. GlaxoSmithKline Medicines Research Centre

7. Stevenage

Abstract

Highly substituted novel 2-spiropiperidines, which are scaffolds suitable for drug discovery or natural products synthesis, were synthesized in a simple one-pot or two-pot procedure.

Funder

University of York

GlaxoSmithKline

Erasmus+

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/OB/C8OB01272E

Reference27 articles.

1. Synthesis of highly substituted 2-spiropiperidines

2. Histrionicotoxins: Roentgen-Ray Analysis of the Novel Allenic and Acetylenic Spiroalkaloids Isolated from a Colombian Frog, Dendrobates histrionicus

3. Nankakurine A, a Novel C16N2-Type Alkaloid from Lycopodium hamiltonii

4. Nankakurine B, a New Alkaloid from Lycopodium hamiltonii and Revised Stereostructure of Nankakurine A

5. Pinnaic acid and tauropinnaic acid: Two novel fatty acids composing a 6-azaspiro[4.5]decane unit from the Okinawan bivalve Pinna muricata

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