Base-promoted diastereoselective α-alkylation of borane N-((S)-1′-phenylethyl)azetidine-2-carboxylic acid ester complexes-Reference-Cited by-同舟云学术

Base-promoted diastereoselective α-alkylation of borane N-((S)-1′-phenylethyl)azetidine-2-carboxylic acid ester complexes

Published:2018 Issue:32 Volume:16 Page:5833-5845
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Tayama Eiji¹²³⁴⁵^ORCID,Nishio Ryotaro⁶³⁴⁵,Kobayashi Yoshiaki⁶³⁴⁵

Affiliation:

1. Department of Chemistry

2. Faculty of Science

3. Niigata University

4. Niigata

5. Japan

6. Graduate School of Science and Technology

Abstract

Synthesis of optically-active α-substituted azetidine-2-carboxylic acid esters starting from (S)-1-phenylethylamine was successfully demonstrated via diastereoselective N-boration followed by α-alkylation.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/OB/C8OB01395K

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