Asymmetric [3+2] spiroannulation of pyrazolone-derived Morita–Baylis–Hillman carbonates with alkynyl ketones: facile access to spiro[cyclopentadiene-pyrazolone] scaffolds-Reference-Cited by-同舟云学术

Asymmetric [3+2] spiroannulation of pyrazolone-derived Morita–Baylis–Hillman carbonates with alkynyl ketones: facile access to spiro[cyclopentadiene-pyrazolone] scaffolds

Published:2022 Issue:68 Volume:58 Page:9504-9507
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Wei Xingfu¹,Huang Yue¹,Wang Wenyao¹,Wei Shiqiang¹,Qu Jingping¹^ORCID,Wang Baomin¹^ORCID

Affiliation:

1. State Key Laboratory of Fine Chemicals, Department of Pharmaceutical Sciences, School of Chemical Engineering, Dalian University of Technology, Dalian 116024, People's Republic of China

Abstract

An organocatalyzed asymmetric [3+2] spiroannulation reaction of pyrazolone-derived MBH carbonates with alkynyl ketones was described, affording chiral spiro[cyclopentadiene-pyrazolone] scaffolds in good yields with high degrees of enantiocontrol.

Funder

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/CC/D2CC02963D

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