Palladium catalyzed asymmetric allylic alkylation of isoquinolinedione derivatives in the preparation of quaternary carbon stereocenters
Author:
Affiliation:
1. State Key Laboratory of Functions and Applications of Medicinal Plants
2. Guizhou Provincial Engineering Technology Research Center for Chemical Drug R&D
3. School of Pharmacy
4. Guizhou Medical University
5. Guiyang 550004
Abstract
A highly enantioselective allylic alkylation of isoquinolinedione derivatives under palladium catalysis was developed in the preparation of quaternary carbon stereocenters.
Funder
National Natural Science Foundation of China
State Key Laboratory of Drug Research
Guizhou Science and Technology Department
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/OB/D0OB00765J
Reference50 articles.
1. Synthetic approaches to the 2011 new drugs
2. The Catalytic Enantioselective Construction of Molecules with Quaternary Carbon Stereocenters
3. Catalytic Enantioselective Construction of All-Carbon Quaternary Stereocenters
4. Catalytic enantioselective synthesis of quaternary carbon stereocentres
5. Catalytic Enantioselective Construction of Quaternary Stereocenters: Assembly of Key Building Blocks for the Synthesis of Biologically Active Molecules
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