Hydrolytic dynamic kinetic resolution of racemic 3-phenyl-2-oxetanone to chiral tropic acid-Reference-Cited by-同舟云学术

Hydrolytic dynamic kinetic resolution of racemic 3-phenyl-2-oxetanone to chiral tropic acid

Published:2024 Issue:9 Volume:14 Page:6121-6126
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Kawasaki Midori¹^ORCID,Shirai Takahiro²^ORCID,Yatsuzuka Kenji¹^ORCID,Shirai Ryuichi¹^ORCID

Affiliation:

1. Faculty of Pharmaceutical Sciences, Doshisha Women's College of Liberal Arts, 97-1 Minamihokotate, Kodo, Kyotanabe, Kyoto 610-0395, Japan

2. Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan

Abstract

The hydrolytic dynamic kinetic resolution of racemic 3-phenyl-2-oxetanone using a chiral PTC and water-free basic anion exchange resin as the hydroxide ion donor was achieved.

Funder

Pharmaceutical Society of Japan

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D3RA08594E

Reference18 articles.

1. Synthesis, characterization and pharmacological profile of tropicamide enantiomers

2. Differential analgesic activity of the enantiomers of atropine derivatives does not correlate with their muscarinic subtype selectivity

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4. Chirality of Natural Products : Hyoscyamine and Scopolamine

5. Enzymatic kinetic resolution of tropic acid

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