Monitoring clinical levels of heparin in human blood samples with an indicator-displacement assay-Reference-Cited by-同舟云学术

Monitoring clinical levels of heparin in human blood samples with an indicator-displacement assay

Published:2015 Issue:10 Volume:51 Page:1953-1956
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Francoia Jean-Patrick¹²³⁴,Pascal Robert¹²³⁴,Vial Laurent¹²³⁴

Affiliation:

1. Institut des Biomolécules Max Mousseron

2. UMR 5247 CNRS – Université de Montpellier

3. 34296 Montpellier cedex 5

4. France

Abstract

Herein, we report a simple assay – involving the displacement of a new designed dye from a dendrigraft surface – that allows for the first time the turn-ON fluorescent detection and quantification of heparin in human blood at clinically relevant levels.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2015/CC/C4CC08563A

Reference38 articles.

1. Heparin-Protein Interactions

2. Management of Venous Thromboembolism

3. Coagulation assays and anticoagulant monitoring

4. Problems In Laboratory Monitoring Of Heparin Dosage

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