Structures, chemotaxonomic significance, cytotoxic and Na+,K+-ATPase inhibitory activities of new cardenolides from Asclepias curassavica-Reference-Cited by-同舟云学术

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Structures, chemotaxonomic significance, cytotoxic and Na+,K+-ATPase inhibitory activities of new cardenolides from Asclepias curassavica

Published:2014 Issue:44 Volume:12 Page:8919-8929
ISSN:1477-0520
Container-title:Org. Biomol. Chem.
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Zhang Rong-Rong¹²³⁴,Tian Hai-Yan¹²³⁴,Tan Ya-Fang¹²³⁴,Chung Tse-Yu⁵⁶⁷,Sun Xiao-Hui¹²³⁴,Xia Xue¹²³⁴,Ye Wen-Cai¹²³⁴,Middleton David A.⁸⁹¹⁰,Fedosova Natalya¹¹¹²¹³,Esmann Mikael¹¹¹²¹³,Tzen Jason T. C.⁵⁶⁷,Jiang Ren-Wang¹²³⁴

Affiliation:

1. Institute of Traditional Chinese Medicine and Natural Products

2. College of Pharmacy

3. Jinan University

4. Guangzhou 510632, P. R. China

5. Graduate Institute of Biotechnology

6. National Chung-Hsing University

7. Taichung 40227, China

8. Department of Chemistry

9. University of Lancaster

10. Lancaster LA1 4YB, UK

11. Department of Biomedicine

12. Aarhus University

13. Aarhus, Denmark

Abstract

New cardenolides with potent cytotoxic and Na⁺,K⁺-ATPase inhibitory activities were isolated from the ornamental milkweed Asclepias curassavica.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/OB/C4OB01545B

Reference35 articles.

1. Structural insights into the high affinity binding of cardiotonic steroids to the Na+,K+-ATPase

2. Cardiac Glycosides as Novel Cancer Therapeutic Agents

3. Chemical defence in chewing and sucking insect herbivores: Plant-derived cardenolides in the monarch butterfly and oleander aphid

4. Calotropin, a Cytotoxic Principle Isolated from Asclepias curassavica L.

5. 3'-epi-19-Norafroside and 12.BETA.-Hydroxycoroglaucigenin from Asclepias curassavica.

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2. Spatial metabolomics reveal divergent cardenolide processing in the monarch (Danaus plexippus) and the common crow butterfly (Euploea core);Molecular Ecology Resources;2023-03-31

3. New Structures, Spectrometric Quantification, and Inhibitory Properties of Cardenolides from Asclepias curassavica Seeds;Molecules;2022-12-23

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5. Molecular Networking and On-Tissue Chemical Derivatization for Enhanced Identification and Visualization of Steroid Glycosides by MALDI Mass Spectrometry Imaging;Analytical Chemistry;2022-11-08

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