In vitro studies on the selective cytotoxic effect of luminescent Ru(ii)-p-cymene complexes of imidazo-pyridine and imidazo quinoline ligands

Author:

Selvam Pravinkumar1ORCID,De Sourav12ORCID,Paira Priyankar1ORCID,Kumar S. K. Ashok1ORCID,Kumar R Selva3ORCID,Moorthy Anbalagan4,Ghosh Arjita4,Kuo Yung-Chih2,Banerjee Subhasis5,Jenifer Shantha Kumar6

Affiliation:

1. Department of Chemistry, School of Advanced Sciences, Vellore Institute of Technology, Vellore-632014, Tamil Nadu, India

2. Department of Chemical Engineering, National Chung Cheng University, Chia-Yi, Taiwan 62102, Republic of China

3. Department of Chemistry, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Science (SIMATS), Chennai – 602105, Tamil Nadu, India

4. Department of Biotechnology, School of Bioscience & Technology, Vellore Institute of Technology, Vellore 632014, Tamil Nadu, India

5. Department of Pharmaceutical Chemistry, Gupta College of Technological Sciences. Asansol-713301, West Bengal, India

6. DST Unit of Nanoscience (DST UNS) and Thematic Unit of Excellence (TUE), Department of Chemistry, Indian Institute of Technology Madras, Chennai – 600 036, India

Abstract

In recent years, Ru(ii) complexes have gained high importance in medicinal chemistry due to their significant anti-cancer activities, which are directly related to their DNA binding ability.

Funder

Vellore Institute of Technology, Vellore

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

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