A practical and cost-effective approach to polysubstituted pyrimidine derivatives <i>via</i> DBU mediated redox isomerization of propargyl alcohol and subsequent N–C–N fragment condensation-Reference-Cited by-同舟云学术

A practical and cost-effective approach to polysubstituted pyrimidine derivatives via DBU mediated redox isomerization of propargyl alcohol and subsequent N–C–N fragment condensation

Published:2022 Issue:22 Volume:46 Page:10603-10610
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

De Rimpa¹,Sengupta Utsav¹^ORCID,Savarimuthu Antony²,Misra Souvik¹,Nanda Jayanta³,Bera Mrinal K.¹^ORCID

Affiliation:

1. Department of Chemistry, Indian Institute of Engineering Science and Technology (IIEST), Shibpur, PO- Botanic Garden, Howrah-711 103, (WB), India

2. Department of Chemistry, St. Xavier's College (Autonomous), Palayamkottai, Tamil Nadu-627 002, India

3. Department of Chemistry, University of North Bengal, Darjeeling-734013, West Bengal, India

Abstract

A straightforward, efficient yet effortless approach for the synthesis of structurally important triarylated pyrimidine derivatives has been successfully developed using secondary propargyl alcohol and commercially available amidines under mild basic conditions.

Funder

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/NJ/D2NJ00586G

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3. Pyrimidine as Constituent of Natural Biologically Active Compounds