Antibacterial activity and mechanism of action of a thiophenyl substituted pyrimidine derivative-Reference-Cited by-同舟云学术

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Antibacterial activity and mechanism of action of a thiophenyl substituted pyrimidine derivative

Published:2019 Issue:19 Volume:9 Page:10739-10744
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Fang Zhiyuan¹²³,Li Yanan⁴⁵⁶³,Zheng Yuanyuan⁷⁸⁹¹⁰³,Li Xiaomei¹²³,Lu Yu-Jing¹¹¹²¹³³,Yan Siu-Cheong⁷⁸⁹¹⁰³,Wong Wing-Leung¹⁴¹⁵¹⁶³,Chan Kin-Fai⁷⁸⁹¹⁰³,Wong Kwok-yin⁷⁸⁹¹⁰³,Sun Ning¹²³⁷⁸^ORCID

Affiliation:

1. The Fifth Affiliated Hospital of Guangzhou Medical University

2. Guangzhou 510700

3. P. R. China

4. Department of Pharmacy

5. The Fifth Affiliated Hospital of Sun Yat-sen University

6. Zhuhai

7. State Key Laboratory of Chemical Biology and Drug Discovery

8. Department of Applied Biology and Chemical Technology

9. The Hong Kong Polytechnic University

10. Kowloon

11. Department of Pharmaceutical Engineering

12. Guangdong University of Technology

13. Guangzhou 510006

14. School of Biotechnology and Health Sciences

15. Wuyi University

16. Jiangmen 529020

Abstract

F20 exhibits strong antibacterial activity through interacting with FtsZ.

Funder

National Natural Science Foundation of China

Research Grants Council, University Grants Committee

Innovation and Technology Commission

Hong Kong Polytechnic University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RA/C9RA01001G

Reference30 articles.

1. Antibiotic resistance and molecular characterization of diarrheagenic Escherichia coli and non-typhoidal Salmonella strains isolated from infections in Southwest China

2. Antibiotics: A New Hope

3. Microbial pathogenicity and virulence mediated by integrons on Gram-positive microorganisms

4. New insights into meticillin-resistant Staphylococcus aureus (MRSA) pathogenesis, treatment and resistance

5. Bacterial cell division as a target for new antibiotics

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1. The study of honokiol as a natural product-based antimicrobial agent and its potential interaction with FtsZ protein;Frontiers in Microbiology;2024-07-22

2. Screening Studies of the Antimicrobial Activity of the Pyrimidine Compound 2,2-[6-Bromo-2,4-Dioxoquinazoline-1,3(2H)diyl]bis(N-Carbamimidoylacetamide);Antibiot Khimioter = Antibiotics and Chemotherapy;2024-04-15

3. Synthesis and in vitro evaluation of antibacterial and antibiofilm activities of novel triphenylphosphonium‐functionalized substituted pyrimidines;Chemical Biology & Drug Design;2024-02

4. Loss in the Antibacterial Ability of a PyrR Gene Regulating Pyrimidine Biosynthesis after Using CRISPR/Cas9-Mediated Knockout for Metabolic Engineering in Lactobacillus casei;Microorganisms;2023-09-22

5. Recent medicinal approaches of novel pyrimidine analogs: A review;Heliyon;2023-06

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