Zn(<scp>ii</scp>)-catalysed enantioselective addition of alcohols and <i>tert</i>-butyl hydroperoxide to isatin-derived <i>N</i>-Boc ketimines-Reference-Cited by-同舟云学术

Zn(ii)-catalysed enantioselective addition of alcohols and tert-butyl hydroperoxide to isatin-derived N-Boc ketimines

Published:2023 Issue:46 Volume:59 Page:7096-7099
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Hou Jiaqi¹,Xue Leipeng¹,Yu Tianxu¹,Li Jiahui¹,Yu Shibo¹^ORCID,Yao Chao¹,Li Yue-Ming¹^ORCID

Affiliation:

1. State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, 300350, China

Abstract

A chiral zinc complex-catalysed addition of alcohols and tert-butyl hydroperoxide to isatin-derived N-Boc ketimines provided the desired products in up to 99% yield and up to 99% ee.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CC/D3CC01527K

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