Knowledge of the Proposed Chemical Mechanism of Action and Cytochrome P450 Metabolism of Antimalarial Trioxanes Like Artemisinin Allows Rational Design of New Antimalarial Peroxides-Reference-Cited by-同舟云学术

Knowledge of the Proposed Chemical Mechanism of Action and Cytochrome P450 Metabolism of Antimalarial Trioxanes Like Artemisinin Allows Rational Design of New Antimalarial Peroxides

Published:2004-04-24 Issue:6 Volume:37 Page:397-404
ISSN:0001-4842
Container-title:Accounts of Chemical Research
language:en
Short-container-title:Acc. Chem. Res.

Author:

Posner Gary H.¹,O'Neill Paul M.¹

Affiliation:

1. Department of Chemistry, The Johns Hopkins University, Baltimore, Maryland 21218, The Johns Hopkins Malaria Research Institute, Bloomberg School of Public Health, Baltimore, Maryland 21205, and Departments of Chemistry and Pharmacology, The University of Liverpool, Liverpool L69 7ZD, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

General Medicine,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ar020227u

Reference54 articles.

1. The Future Outlook of Antimalarial Drugs and Recent Work on the Treatment of Malaria

2. Clinical status and implications of antimalarial drug resistance

3. Qinghaosu (Artemisinin): an Antimalarial Drug from China

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