Organotin(iv) carboxylate derivatives as a new addition to anticancer and antileishmanial agents: design, physicochemical characterization and interaction with Salmon sperm DNA
Author:
Affiliation:
1. Department of Chemistry
2. COMSATS Institute of Information Technology
3. Abbottabad, Pakistan
4. Quaid-i-Azam University
5. Islamabad 45320, Pakistan
6. Loughborough University
7. Loughborough, UK
8. Centre for Advanced Drug Research
Abstract
The compounds interact with DNA via the intercalative mode of interaction. They show strong antibacterial, anticancer and antileishmanial activities.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2014/RA/C4RA10487K
Reference66 articles.
1. Novel Organotin(IV) Schiff Base Complexes with Histidine Derivatives: Synthesis, Characterization, and Biological Activity
2. Phenanthroline Derivatives with Improved Selectivity as DNA-Targeting Anticancer or Antimicrobial Drugs
3. Organotin(IV)n+ complexes formed with biologically active ligands: equilibrium and structural studies, and some biological aspects
4. Organometallic compounds in oncology: implications of novel organotins as antitumor agents
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