Highly stereoselective nickel-catalyzed difluoroalkylation of aryl ketones to tetrasubstituted monofluoroalkenes and quaternary alkyl difluorides-Reference-Cited by-同舟云学术

Highly stereoselective nickel-catalyzed difluoroalkylation of aryl ketones to tetrasubstituted monofluoroalkenes and quaternary alkyl difluorides

Published:2019 Issue:40 Volume:10 Page:9285-9291
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Li Chao¹²³⁴⁵,Cao Yi-Xuan¹²³⁴⁵,Jin Ruo-Xing¹²³⁴⁵^ORCID,Bian Kang-Jie¹²³⁴⁵,Qin Zi-Yang¹²³⁴⁵,Lan Quan¹²³⁴⁵,Wang Xi-Sheng¹²³⁴⁵^ORCID

Affiliation:

1. Hefei National Laboratory for Physical Sciences at the Microscale

2. Department of Chemistry

3. Center for Excellence in Molecular Synthesis of CAS

4. University of Science and Technology of China

5. Hefei

Abstract

A nickel-catalyzed difluoroalkylation of aryl ketones to furnish highly stereo-defined tetrasubstituted monofluoroalkenes or quaternary alkyl difluorides has been established.

Funder

Chinese Academy of Sciences

National Basic Research Program of China

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/SC/C9SC02806D

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