gem-Difluoroalkylation of Cyclic Ethers Enabled by Cobalt-Catalyzed C(sp3)–H Oxidation under Mild Conditions

Author:

Yang Jingjie1,Wang Zhiming2ORCID,Zhang Yiheng3,Wang Yurong3,Yao Weijun1ORCID,Gao Kai2ORCID

Affiliation:

1. School of Chemistry and Chemical Engineering, Zhejiang Sci-Tech University, Hangzhou, Zhejiang 310018, People’s Republic of China

2. Advanced Research Institute and School of Pharmaceutical Science, Taizhou University, Taizhou, Zhejiang 318000, People’s Republic of China

3. School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, People’s Republic of China

Funder

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Publisher

American Chemical Society (ACS)

Reference45 articles.

1. Fluorine in Pharmaceuticals: Looking Beyond Intuition

2. Fluorine in medicinal chemistry

3. Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design

4. Alexandrov, V.; Bowen, C. A.; Hanania, T. G.; Powell, N. A. Preparation of isochromanamine derivatives and analogs for use as nervous system agents. WO Patent 2018023070 A1, 2018.

5. aInoue, M.; Ogoshi, Y.; Furukawa, T.; Machida, T.; Mitani, I.; Harada, K.; Nakagawa, Y.; Yamaoka, N. Preparation of tetrahydrobenzofurodiazepinone compounds as Pim-1 inhibitors and pharmaceutical applications thereof. WO Patent 2022075240 A1, 2022.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3