Practical and economic lithiations of functionalized arenes and heteroarenes using Cy2NLi in the presence of Mg, Zn or La halides in a continuous flow-Reference-Cited by-同舟云学术

Practical and economic lithiations of functionalized arenes and heteroarenes using Cy2NLi in the presence of Mg, Zn or La halides in a continuous flow

Published:2015 Issue:11 Volume:6 Page:6649-6653
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Becker Matthias R.¹²³⁴,Ganiek Maximilian A.¹²³⁴,Knochel Paul¹²³⁴

Affiliation:

1. Ludwig-Maximilians-Universität München

2. Department Chemie

3. 81377 München

4. Germany

Abstract

The economic amide base lithium dicyclohexylamide (Cy₂NLi) undergoes fast (40 s) and convenient (0 °C) in situ trapping flow metalations of a broad range of functionalized aromatics in the presence of various metal salts.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/SC/C5SC02558C

Reference51 articles.

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