Author:
Ashikari Yosuke,Guan Kaiteng,Nagaki Aiichiro
Abstract
We achieved an integration of a lithiation of aryl bromides, a zincation of thus-generated aryllithiums, and a Negishi coupling of the arylzinc with an aryl halide in one flow. Taking advantages of flow microreactors, biaryls bearing a wide range of functional groups, especially biaryls bearing multiple electrophilic-functionalities were synthesized.
Funder
Japan Society for the Promotion of Science
Japan Agency for Medical Research and Development
Core Research for Evolutional Science and Technology
New Energy and Industrial Technology Development Organization
Ogasawara Foundation
JKA Foundation
Kyoto Technoscience Center
Cited by
3 articles.
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